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http://projects.csail.mit.edu/courseware/?term=national-junior-honor-society-essay-example national junior honor society essay example Lenalidomide is more potent and has a more favorable safety profile over thalidomide. 34 the combination of lenalidomide, bortezomib, and dexamethasone has emerged as the one of the most commonly used induction regimens in the treatment of transplant-eligible patients with myeloma. Phase iii trials showed that lenalidomide in combination with dexamethasone produced higher response rates and a longer time to progression than dexamethasone alone in relapsed and refractory patient care process chronic myeloid leukemia patient assessment. •• review laboratory values and determine the stage of cml depending on the percent blasts in the peripheral blood or bone marrow. •• review medical history, including patient's age, comorbid conditions and current medications to avoid drug–drug interactions. Therapy evaluation. •• if hematologic, cytogenetic and molecular goals are not achieved, determine whether a change in medication is warranted. •• if the patient experiences intolerance to therapy including any severe adverse effects, a change in medication may be warranted. •• determine whether one of the first-line tkis may be more cost-effective than the other agents. Care plan development. •• discuss the importance of medication adherence and longterm outcomes. •• address any concerns about the selected medication including cost and management of adverse effects. Follow-up evaluation. •• tki therapy should be frequently monitored. Follow-up may be scheduled every 3 months to determine whether goals of therapy are being met. •• out of office follow up (ie, phone calls) may be helpful to reinforce the importance of adherence and to identify and manage any adverse effects. Chronic lymphocytic leukemia patient assessment. •• review history of present illness, physical exams, and laboratory values to determine whether immediate treatment is necessary. Therapy evaluation. •• depending on the therapy, assess efficacy, adverse effects, and patient adherence. •• if patients continue to have disease progression, another regimen may be utilized. •• monitor wbc count and signs of infection if the patient is receiving aggressive chemoimmunotherapy. Care plan development. •• address any concerns about the selected medication including cost and management of adverse effects. •• supportive care medication such as remedications for the prevention of infusion reactions, prophylactic trimethoprim– sulfamethoxazole and an antiviral (acyclovir, famciclovir, or valacyclovir) may be recommended for certain medications. Follow-up evaluation. •• asymptomatic patients will be routinely follow-up to determine when they require treatment. •• routine follow-ups during and postchemotherapy will be needed to assess treatment efficacy. Multiple myeloma patient assessment. •• review medical history, including patient's age, comorbid conditions and current medications to determine whether the patient is transplant eligible. Therapy evaluation. •• if patients continue to have disease progression or have relapsed disease, another regimen may be utilized. •• monitor myeloma monoclonal protein in urine and serum, renal function, hemoglobin, and platelets.

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